帕金森病细胞病变过程图形化

In the US alone, at least 500,000 people suffer from Parkinson's disease, a neurological disorder¹ that affects a person's ability to control his or her movement. New technology from the University of Bonn in Germany lets researchers observe the development of the brain cells responsible for the disease. Up until now, research into the brain cells responsible for Parkinson's disease has focused on the function and degeneration of these neurons in the adult and aging brain. The new tissue slicing method, which will be published in the world's only peer-reviewed science video journal, the Journal of Visualized³ Experiments (JoVE), allows scientists to observe the development of these brain cells for the first time. #

"Little is known about the behavior of these neurons during their differentiation⁴ and migration⁵ phase（时期，局面） ," said article author Dr. Sandra Blaess, "and with this technique, we can really observe how these cells behave during development." #

The new technique also makes the cells available for genetic⁶ manipulation, and more information about how these cells develop and function could lead to new treatment options.

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"Being able to visualize² cell development in this area of the brain is exciting," said JoVE Editor Dr. Claire Standen. "The availability of this technique could help scientists understand diseases of the dopaminergic（多巴胺能的） system- such as Parkinson's." #